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Science of Synthesis

Science of Synthesis is one of the most in-depth authoritative information sources available on synthetic methodology. To best meet the needs of the scientific community, Science of Synthesis is published not only in print but also in an electronic format.

The electronic version was developed in co-operation with InfoChem, and under the guidance of an international advisory board, each of whom is a leading expert in electronic information provision. Their knowledge and experience has given us the opportunity to create an interface that is molded to the needs of our users, thus ensuring that Science of Synthesis will be at the heart of the fully integrated laboratory of the future.

The online product makes use of the latest developments in information technology and is equipped with a powerful and user-friendly information-retrieval system to allow substructure, exact structure, reaction, combined keyword and full text searches.

Click here to read a review on the electronic product for Science of Synthesis.

Tailored for Synthetic Chemists

Science of Synthesis is designed as a web-based system that is available through either the internet or a customer's intranet, and uses standard browser technology. This provides the user with the opportunity to tailor the interface to their own personal requirements.
As with the printed work the electronic version presents the information in a logical hierarchy that is ordered according to functional group and product classes, allowing the user to browse an area of interest.

Science of Synthesis will contain information on 18 000 generally applicable experimental procedures, which include 180 000 reactions and 800 000 structures. The electronic product for Science of Synthesis provides a direct path through the mass of primary literature to the pertinent data on a comprehensive range of organic reactions.

 

Integrated products

Integration with Houben–Weyl

Houben–Weyl is a world-renowned reference work, trusted and used by chemists for more than 100 years. Throughout its development this vast reference work has involved prominent chemists from every generation dating back to the early 1800’s. Houben–Weyl is available through the Science of Synthesis interface as an electronic backfile. The inclusion of an exclusive structural template facilitates searching and permits straightforward information retrieval.

Houben–Weyl documents are accessible through searches made in Science of Synthesis, or alternatively the backfile can be searched independently from the content of Science of Synthesis. Houben–Weyl includes some 146 000 product specific experimental procedures, 580 000 structures, along with 700 000 references. The content of Science of Synthesis combined with Houben–Weyl as an electronic backfile offers chemists an unprecedented source of accessible and evaluated experimental information.

The electronic version of Houben–Weyl provides the user with:

  • access to chemistry methodology and data spanning two centuries produced by the finest chemists of each generation
  • a web-based portal that is easy to navigate and utilizes standard browser technology
  • a logical, hierarchical interface that allows the user to browse an area of interest as if it were a book
  • a search engine which uses sophisticated text searching functionalities

The electronic product can also be searched using the Houben–Weyl Guide that presents families of molecules and functional groups in graphical form. By simply clicking on the structures the user is taken directly to the relevant articles, thus allowing users to screen the content rapidly and in a manner that is both intuitive and familiar.

Availability

To address the needs of the user, Science of Synthesis is available on an annual subscription basis and is priced according to the number of potential users that wish to access the database. In order to subscribe please contact our sales representatives for further information.

 

News

Award for
Barry M. Trost

We would like to congratulate Barry M. Trost, Editorial Board Member, Science of Synthesis, on being awarded the Nagoya Gold Medal Prize of Organic Chemistry 2008. The Nagoya Medal Prize (Gold Medal) has been awarded every year since 1995 to an organic chemist who has made significant original contributions to the field, in its broadest sense. The recipient of the Gold Medal 2008, Barry M. Trost, will deliver the Nagoya Medal Award Lecture on October 31, 2008 at Nagoya University in Nagoya, Japan. The Gold Medal Award Lecture is entitled:
1 "Self Assembly of Dinuclear Main Group Catalysts for Asymmetric Synthesis"
2 "Cycloadditions via TMM-Pd Intermediates: New Strategies for Total Synthesis and Asymmetric Induction"

Award for
Eric N. Jacobsen

We would like to congratulate Eric N. Jacobsen, Editorial Board Member, Science of Synthesis, on being awarded the Yamada–Koga Prize 2008 which is awarded every year to a scientist whose research has a major impact in the fields of the synthesis of optically active compounds. The Yamada–Koga Prize will be awarded to Professor Eric N. Jacobsen on November 14, 2008, at the 18th Symposium on Optically Active Compounds held in Tokyo, Japan.

Awards for
Steven V. Ley

We would like to congratulate Steven V. Ley, Editorial Board Member, Science of Synthesis, on receiving the Prous Institute-Overton and Meyer Award for New Technologies in Drug Discovery, European Federation of Medicinal Chemistry, Vienna (2008) and the Hans Heroff Inhoffen Medal, Helmholtz Zentrum für Infectionsforschung (2008).

Professor
John Colin Tatlow
(1923–2008)

We are very sorry to announce that Professor John Colin Tatlow passed away in the UK on April 9th, 2008. Professor Tatlow was the Editor-in-Chief of the E10 Organo-Fluorine Compounds (Houben–Weyl) series and made a major contribution to fluorine chemistry during his career. He was the recipient of the American Chemical Society Award for Creative Work in Fluorine Chemistry in 1990. We would like to extend our sincere condolences to his family and friends.

Over 18,000
New Reactions
Added to

Science of Synthesis
Version 3.5
New York/Stuttgart – Thieme is pleased to announce that Science of Synthesis Version 3.5 is now available. The electronic information resource now contains 34 volumes, out of what will eventually be a total of 48 volumes. This upgraded version has a total of 195,000 reactions, with over 18,000 new reactions, and holds significant synthetic methods for a wide range of classes of compounds. The newly added content consists of volumes 29 and 31

Volume Publication

Science of Synthesis
Volume 37
We are very pleased to announce the publication of Science of Synthesis Volume 37 [Compounds with One Saturated Carbon¾Heteroatom Bond: Ethers] by Craig J. Forsyth and Eric N. Jacobsen in May 2008. The volume is 992 pages in length and provides a critical review of methods for the synthesis of ethers.

Thieme IUPAC Prize

Congratulations to
F. Dean Toste, recipient of the 2008 Thieme–IUPAC Prize.

Archive

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