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Preface to the 3rd Edition

Click here to view the Preface in pdf format.

The first edition of Protecting Groups was published in 1994 and it was appreciated by undergraduates, graduate students and researchers alike as a critical and didactic complement to the encyclopaedic coverage provided by Greene and Wuts in their monumental Protective Groups in Organic Synthesis. In this new edition I have tried to maintain those elements that were popular in the first: the focus on a relatively small number of commonly used protecting groups, the emphasis on deprotection conditions, and the extensive use of schemes to aid visual retrieval of information. I have also carefully chosen the examples to give a snapshot of organic synthesis for the last decade albeit from the narrow perspective of protecting group chemistry. However, the differences are far more pronounced than the similarities. The book has been reorganised and thoroughly revised and updated. Two new chapters on thiol and phosphate protecting groups have been added and most of the schemes from the first edition have been replaced by more modern examples. The number of schemes has increased from 500 to 1200 and colour has been introduced as an aid to visual retrieval. The number of references has also swollen from 1200 to 2270 with emphasis given to literature covering the period 1990-2001. Finally an epilogue containing 25 problems of varying difficulty has been added for the delectation of the curious.

There is a Russian proverb that says you cannot step twice into the same river. These wise words should temper the expectations of anyone contemplating a new edition of a popular book. What worked well the first time may not be so welcome or apposite the second. It is for the reader to decide if time and the river have been kind.


Acknowledgements

I would like to reiterate my special thanks to Dr Krzysztof Jarowicki for his advice and assistance, and Dr Joe Richmond for his expert editing of the manuscript.


PHILIP J. KOCIENSKI
Leeds University
October, 2003

 

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The best selling 3rd edition of P.J. Kocienski's "Protecting Groups" is now also available as a softcover version. Click here for more info and to order your personal copy for just € 69.95 / $ 89.95.

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